The Xie lab always seek for talented and motivated PhD student and Postdoctoral scholar candidates. Interested individuals are encouraged to arrange a discussion during the following events, in which Chong and/or group members will present. 9/11 - 14, 2017, Workshop on Physical Limits to Measurements in Neurobiology, HHMI Janelia Research Center. Oct 11 - 14, 2017, BMES, Phoenix Nov 1 - 2, 2017, IEEE Brain Initiative Workshop, Glasgow Nov 8 - 12, 2017, SfN Meeting, DC Mar 25 - 30 2018, Gordon Conference, Galveston
Our paper "Nanoelectronic Coating Enabled Versatile Multifunctional Neural Probes" is published on Nano Letters. In this paper, we report a novel multifunctional neural probe platform realized by applying ultrathin nanoelectronic coating on the surfaces of conventional microscale devices such as optical fibers and micropipettes. We hope to provides a low-cost, versatile approach to construct multifunctional neural probes that can be applied to both fundamental and translational neuroscience.
Chong is awarded a R01 from NINDS for developing reliable chronic neural recording. With this support, we will design and optimize neural probes with dimensions, surgical footprint and mechanical compliance matching that of the living tissue. We hope to mitigate in-vivo device failure modes and suppress tissue reactions to achieve chronically reliable electrical recording. See the department news for more details.
Lan is awarded a R21 from NINDS to study the hemodynamic and neural consequences of peri-infarct depolarization after ischemic stroke. We will combine our ultraflexible NET electrodes with advanced functional imaging techniques in the Dunn lab to simultaneous map neural activity and hemodynamic parameters in a mouse stroke model with fine control on the lesion size and location. This marks our first application of NET electrodes for disease models. Thank you NINDS for the funding support!
Alex Huk (Professor of Neuroscience) and Chong Xie are awarded the CNS (college of Natural Science) Catalyst Grant to officially start their collaboration in novel neural interface in non-human primates. We will have so much fun playing with marmosets and understanding their neural circuit.
Chong is awarded a 3-year Welch Foundation research grant for "Probing the in vivo Chemistry in the Behaving Brain". Thank you very much, Welch Foundation! We are excited to explore chemistry in behaving mouse brain!
Our group's first paper, "Ultraflexible nanoelectronic probes form reliable, glial scar–free neural integration", is published on Science advances with a cover image. We showed in this work by engineering the dimension and rigidity of neural probes it became possible to reliably record and track individual neurons over long term and to form seamless integration with living brain.
In collaboration with Robert J. Buchanan, MD, Chong is awarded a small Catalyst fund from the Texas Health Catalyst for the project "Fibrosis-Free Localized Drug Delivery Implant for Chronic Neuropathic Pain Management".
We delivered three talks at MRS fall meeting 2016, in the Symposium BM4 : Materials and Manufacturing of Biointerface Devices and Stretchable Electronics. Lan presented "Subcellular, Ultra-Flexible Nanoelectronic Probes Form Reliable, Glial Scar Free Neural Integration"; Zhengtuo presented "Ultra-Thin, Nanoelectronic Coating Devices for Versatile Multimodal Neural Probes" and Xiaoling presented "Pushing the Dimensional Limits of Implanted Neural Electrodes". We all enjoyed the conference.
Chong and Lan attended the society of neuroscience meeting 2016 at San Diego. Lan presented our ultra-flexible electrode work at the nano-symposium "new electrode technology". This is the first time we reported our work on national conferences and we are every excited to share it with the community. Thanks very much the organizer for inviting us to speak there!