Multiphoton Microscopy of Nanoshells

MULTIPHOTON MICROSCOPY OF NANOSHELLS
Summary

This project seeks to develop nanoshells as combined luminescence imaging and photothermal therapy agents of tumors. Gold nanoshells (dielectric silica core/gold shell) are a novel class of hybrid metal nanoparticles whose unique optical properties have spawned new applications including more sensitive molecular assays and cancer therapy. We have recently reported that nanoshells (NS) glow brightly when excited by near-infrared light. This bright luminescence enables nanoshells as contrast agents for biological imaging applications.
This project represents a collaboration with researchers from Nanospectra Biosciences and UT Austin.

Collaborators:

Jon Schwartz, PhD, Nanospectra Biosciences
Don Payne, Nanospectra Biosciences
Andrew Dunn, PhD, Biomedical Engineering, University of Texas

Funding:

American Society for Laser Medicine and Surgery. PI: James W. Tunnell