Development and Manufacturing of Fiberoptic Microneedle Devices for Cosmetic and Cancer Treatments

Sponsor: Center for Innovative Technology; Commonwealth Research Commercialization Fund
Performance Period: 1/6/2014-1/5/2015,
PI: Chris Rylander, co-PI: John Robertson, Post-doc: Katelyn Colacino

Our goals are to: 1) manufacture prototype parallel arrays of FMDs for laser fat removal, and, 2) demonstrate the superior capabilities of FMDs vs. conventional laser lipolysis methods. To achieve these goals, we will carry out the following specific aims:

Specific Aim 1: Design and manufacture prototype FMDs for demonstration of laser fat removal.

Specific Aim 2: Evaluate performance of FMD prototypes in excised pig skin.

Specific Aim 3: Evaluate FMD fat removal vs. conventional laser fat removal through a comparative study with in vivo pig models.

Fiberoptic Microneedle Device (FMD) schematic illustration of (top) Alternative design #1 using compression between two rigid plates, and (bottom) Alternative design #2 utilizing layered elastomeric ferrule.